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Science book

Cancer evolution is an example of competitive evolution. It is a warning that competition (darwinian evolution) is not the way to further evolution. Understand this for the sake of our planet and ourselves...
As a book on cancer evolution, the selfish cell deals with innovative concepts in evolutionary biology. Additionally, new ideas on cancer treatments are forwarded to researchers.

energy restriction therapy

what do we know about evolution?

What do we know about biological evolution?

After eight years spent studying a 1.8-million-year-old skull uncovered in the Republic of Georgia, scientists have made a discovery that may rewrite the evolutionary history of our human genus Homo. It would be a simpler story with fewer ancestral species.

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mitochondrion: the crossroad

A paper in pubmed  contains a new mechanistic explanation on how the mitochondria are involved in cancer and other serious diseases.

The study is entitled: "Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer."

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Stem cells mitocondria in cancer

A recent research indicates that the tumorigenic potential of stem cells depend on the degree of activation of their mitochondria. Recent additional data indicate that somatic cells could even become stem cells at the advancing front of carcinomas..maybe dependently on the status of their mitochondria?

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Groundbreaking insight in biology?

A few times ago, surfing the internet, I hit a real groundbreaking piece of information. After that, I attempted a few experiments in my own lab. Today, I must admit, I am not finished with speculations about that topic. My data cannot confirm nor discredit what Dr. Douglas Robinson, as the author of this original research and relative patent, allegedly affirms.

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Infectious agents in cancer

viruses

Physicians all around the globe agree that cancer should not be considered a contagious disease, in the sense that “a person can not take cancer from one having it”. Nonetheless various infectious agents, especially viruses, are recognised carcinogens. A clear confirmation of that is the fact that this year Nobel Prize for Medicine granted to cancer viruses discoverers. Viral agents of various type are clearly associated with human malignancies.

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newsflash

Transmissible cancer

A study in the scientific journal Science describes a form of cancer that is transmissible among dogs. This could open up to speculations about trasmissibility of cancer in general. Are there now more concerns than it is usually appraised..

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experimental models of cancer research

 

A fundamental limitation in cancer research is that results obtained in animal models seldom are repeatable in humans. A huge amount of resources so far have been used to find cures for mice, rats and other animals employed in research just to find out at the end of years of research that in humans the story ended up differently. And from an ethical point of view, how much suffering have been caused to innocent animal creatures for nothing more than speculative knowledge?

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chronic inflammation leads to cancer

inflammation

Yesterday I was in the audience at a seminar on infectious diseases. A speaker was reporting a case of a patient died of a lymphoma after he had suffered for many years of untreated stongiloydosis. He went to the hostipal when the lymphoma had become devastating. Therapies were ineffective at that point.

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Reform Clinical Trials

clinical trials

Which drugs, remedies, devices are safe and effective and are to be licensed into the market? This is a crucial question in medicine economics and more. Scientific medical governament agencies exist (like the FDA, the EMA and the like) that should scrutinize and answer to this question. They do so after results of pre-clinical and clinical trials. This is in principle a very sound system that exist to protect both the health and the money of citizens. Why then criticize it? What is wrong with it?

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